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Flexible Ultrasound Patch Could Make it Easier to Inspect Damage in Odd-Shaped Structures

March 23, 2018

Researchers have developed a stretchable, flexible patch that could make it easier to perform ultrasound imaging on odd-shaped structures, such as engine parts, turbines, reactor pipe elbows and railroad tracks—objects that are difficult to examine using conventional ultrasound equipment. The ultrasound patch is a versatile and more convenient tool to inspect machine and building parts for defects and damage deep below the surface.

New Online Tool Gives 3D View of Human Metabolic Processes

February 27, 2018

A new computational resource called Recon3D provides a 3D view of genes, proteins and metabolites involved in human metabolism. Researchers used the tool to map disease-related mutations on proteins and also probed how genes and proteins change in response to certain drugs. The work provides a better understanding of disease-causing mutations and could enable researchers to discover new uses for existing drug treatments.

Supercomputers Aid Discovery of New, Inexpensive Material to Make LEDs with Excellent Color Quality

February 19, 2018

Computers have helped researchers develop a new phosphor that can make LEDs cheaper and render colors more accurately. An international team led by engineers at UC San Diego first predicted the new phosphor using supercomputers and data mining algorithms, then developed a simple recipe to make it in the lab. Unlike many phosphors, this one is made of inexpensive, earth-abundant elements and can easily be made using industrial methods. As computers predicted, the new phosphor performed well in tests and in LED prototypes.

UC San Diego Innovator in Data Storage Technologies Elected to National Academy of Engineering

February 9, 2018

Back in 1956, IBM built the first disk drive. It was the size of two refrigerators and held a total of five megabytes—enough storage capacity to handle about 30 seconds of video. That’s a stark contrast to today’s hard drives, which can hold tens of terabytes of data and fit in the palm of your hand. One of the key innovators who helped drive this remarkable evolution is Eric Fullerton, a professor of electrical and computer engineering and nanoengineering at UC San Diego.

Recycling and Reusing Worn Cathodes to Make New Lithium Ion Batteries

January 25, 2018

Nanoengineers at the University of California San Diego have developed an energy-efficient recycling process that restores used cathodes from spent lithium ion batteries and makes them work just as good as new. The process involves harvesting the degraded cathode particles from a used battery and then boiling and heat treating them. Researchers built new batteries using the regenerated cathodes. Charge storage capacity, charging time and battery lifetime were all restored to their original levels.

Researchers Develop a Remote-Controlled Cancer Immunotherapy System

January 15, 2018

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells.

Macrophage Nanosponges Could Keep Sepsis In Check

January 4, 2018

Researchers at UC San Diego have developed macrophage "nanosponges"—nanoparticles cloaked in the cell membranes of macrophages—that can safely remove sepsis-causing molecules from the bloodstream. In lab tests, these macrophage nanosponges improved survival rates in mice with sepsis.

Less Than Skin Deep: Humans Can Feel Molecular Differences Between Nearly Identical Surfaces

December 13, 2017

How sensitive is the human sense of touch? Sensitive enough to feel the difference between surfaces that differ by just a single layer of molecules, a team of researchers at the University of California San Diego has shown.

Updated Brain Cell Map Connects Various Brain Diseases to Specific Cell Types

December 11, 2017

Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer’s, Parkinson’s, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers have identified 35 different subtypes of neurons and glial cells and discovered which of these subtypes are most susceptible to common risk factors for different brain diseases.

Experimental Drug Blocks Toxic Ion Flow Linked to Alzheimer’s Disease

December 5, 2017

A new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer’s disease. The molecule, called anle138b, works by stopping toxic ion flow in the brain that is known to trigger nerve cell death. Scientists envision that this drug could be used to treat Alzheimer’s and other neurodegenerative diseases such as Parkinson’s and ALS.
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